11/03/2013

Metformin (Glucophage) is a drug of choice for type 2 diabetes (non-insulin dependent). This is an oral medication that assists in controlling the sugar levels in the blood. It can be used in combination with insulin or other drugs. Metformin can also be used in treating polycystic ovary syndrome although it's not yet officially acknowledged. Just like other medications which have side effects, Metformin side effects should also be watched for.



People who are prescribed to take this medication are required to undergo regular blood sugar level determination. Although metformin does not cause the blood sugar level to drop drastically it may cause severe hypoglycemia if used in combination with other anti-diabetic medications. Common symptoms of hypoglycemia are cool pale skin, cold sweats, anxiety, tremors, peculiar weakness or tiredness, mental confusion, excessive hunger, nausea and headache.



Metformin should never be used for patients with impaired renal functions as it could lead to a serious condition known as lactic acidosis, excessive lactic acid in the blood. People who have liver problems are also potential of developing lactic acidosis. Signs and symptoms of lactic acidosis include rapid breathing, weakness, abdominal pain, vomiting, muscle weakness and other unusual feeling. Kidney and liver functions should be checked at least once a year to prevent future problems.



If you are prescribed to undergo an X-ray examination and an iodinated dye (contrast agent) is necessary, you need to inform your prescribing physician that you are taking Metformin. Normally, the medication has to be stopped prior and 48 hours following the diagnostic procedure. The patient should only resume the medication once kidney function test is done and is found to be in normal condition.



Aside from decreased kidney and liver functions, there are other conditions that contraindicate usage of Metformin. These conditions include diabetic ketoacidosis, dehydration, decreased blood flow to vital organs due to shock, severe infection or trauma, respiratory failure, heart failure, alcoholism, alcoholic intoxication and children under ten years old. Also, people who are sensitive to any of its components should never take the medication without consulting a doctor or pharmacist. If allergic reaction is noticed during the first dose, immediately stop taking the medication.



If you are pregnant or planning to get pregnant and you are taking Metformin, you should inform your physician the soonest possible time. Pregnant women are normally given insulin for a more stable control of blood sugar levels. Lactating women should also avoid Metformin since it may pass into their breast milk.



Among the Metfomin side effects, gut disturbances such as nausea, vomiting, abdominal pain, diarrhea and loss of appetite are the most common that it affects more than 1 in 10 people. Taste distance, a feeling of metallic taste occurs in 1 out of 100 people. Very rare side effects are lactic acidosis, reduced vitamin B12 absorption with chronic use, and skin reaction like itching, flushing or rash.



For more detailed information regarding the side effects of Metformin, you should consult your physician or pharmacist. Avoid taking this medication without the guidance of your physician as it might lead to serious untoward reactions
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