9/14/2013

What is Diabetes Mellitus?



Diabetes mellitus is a chronic health situation in which the body stop working to generate adequate amount of insulin or react strangely to insulin.When we talk about the categorization of diabetes mellitus, it is of three natures, namely,



1. Diabetes



2. Diabetes and Gestational diabetes.



3. Hyperglycemia which is the ultimate outcome for all the three types of diabetes.Pathophysiology of diabetes mellitus is complicated, as the disease is characterized by diverse etiologies but share some related signs,symptoms and complications.



Meaning of pathophysiology



Pathophysiology means the learning of alteration seen in natural mechanical, bodily, and biochemical functions that are maybe caused by a disease or as a  result of an irregular syndrome. The pathophysiology of any given ailment or syndrome give details to  its source,symptoms and effects



Pathophysiology and Diabetes Mellitus



Pathophysiology of diabetes mellitus (all types) is connected to the hormone insulin, which is concealed by the beta cells of the pancreas. This hormone is responsible for keeping the glucose level in the blood. It also allows the body cells to use glucose as the major energy source. though, in a diabetic person, due to the improper insulin metabolism, the body cells and tissues do not utilize the glucose from the blood and as a result of that,it raise the level of hyperglycemia..Within some period of time, elevated glucose level in the bloodstream can lead to critical condition, such as eye disorders, cardiovascular diseases, kidney injury and nerve problems.



In type 1, the pancreas cannot produce sufficient amount of insulin hormone needed by the body. The pathophysiology of type 1 diabetes propose that it is an autoimmune disease, in which the body's own immune system produces secretion of substances that attack the beta cells of the pancreas. As a result, the pancreas give off little or no insulin. The type 1 is more familiar with children and young adults between 20 years. For the reason that it is common among young folks and insulin hormone is used for treatment, the type 1 diabetes is also known as (IDDM) meaning Insulin Dependent Dabetes Mellitus.



The type 2 diabetes mellitus is a normal way to manufacture of insulin hormone except that the body cells are resistant to insulin.For the reason that the body cells and tissues are not sensitive to insulin, glucose stays in the bloodstream. It is ordinarily noticeable by middle-aged adults about 40 years or more.Since the  insulin is not required for the treatment of type 2 diabetes mellitus,so it is regarded as (Adult Onset Diabetes) or (NIIDM) meaning Non-insulin Dependent Diabetes Mellitus. 



On the other hand,gestational diabetes occurs between pregnant women. It is as well triggered due to rise and fall of the hormonal level throughout pregnancy.More often,the blood glucose level come back to where it supposed to be after the baby is born.



Like I said before,the symptoms/signs and effects of the entire three types of diabetes are alike.The apparent clear symptoms contains escalation in dehydration known as (polydipsia),escalation in urination known as (polyuria), escalation in appetite also known as (polyphagia),too much tiredness, mysterious weight loss and body irritation.



In  relation to  the meaning of diabetes mellitus, it is frequently described as a fasting blood glucose level of 126 milligrams per deciliter or more.And as per statistics,the type 2 diabetes is mainly the occurring type,contrast to the remaining two types of diabetes mellitus.



Knowing the correct type of diabetes is very essential to avert rigorous health effects. Subsequent to diagnosis, a medical doctor may prescribe suitable medicine for curing of diabetes, which could contain insulin vaccination or oral insulin medicines, depending on the type of diabetes mellitus the person is a victim of. In addition, healthy lifestyle modifications, especially diet and exercise are recommended for the effective management of symptoms and long-term effects. Since diabetes is a global health issue, studies regarding the pathophysiology of diabetes mellitus are currently in progress in order to minimize its associated health effects.
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